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hrp0082p2-d3-342 | Diabetes (2) | ESPE2014

Prolonged Treatment with Vitamin D Supplementation and High Dose is Necessary to Treat Vitamin D Deficiency/Insufficiency (VDD/I) in Children and Adolescents with Type 1 Diabetes

Xatzipsalti Maria , Dolianiti Maria , Papadopoulou Konstantina , Kouloufakou Penelope , Mitravela Vasiliki-Ioanna , Dracopoulou Maria , Stamogiannou Lela , Vazeou Andriani

Background: Increased frequency of VDD/I has been found in warmer countries over the last years.Objective and hypotheses: To evaluate the response to vitamin D treatment in VDD/I among children and adolescents with type 1 diabetes.Method: Total 25OHvitamin D levels (VDL) were measured in 76 consecutive children and adolescents with type 1 diabetes (36 males, mean age (S.D.) 13.6 (5.09) years, median disease duration ...

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hrp0082p2-d1-373 | Fat Metabolism & Obesity | ESPE2014

Expression Levels of the Growth-Arrest-Specific Transcript 5 in Overweight and Obese Children and Adolescents

Fragouli Terpsihori , Sertedaki Amalia , Farakla Ioanna , Nicolaides Nicolas C , Dracopoulou Maria , Papassotiriou Ioannis , Chrousos George P , Charmandari Evangelia

Background: The noncoding RNA growth-arrest-specific transcript 5 (Gas5) is abundant in cells whose growth has been arrested owing to lack of nutrients or growth factors. Gas5 is a riborepressor of the glucocorticoid receptor, influencing cell survival and metabolic activities during starvation by inhibiting the latters transcriptional activity.Aim: To determine the expression levels of Gas5 in blood samples of obese, overweight and lean children a...

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ESPE Abstracts

Prolonged Treatment with Vitamin D Supplementation and High Dose is Necessary to Treat Vitamin D Deficiency/Insufficiency (VDD/I) in Children and Adolescents with Type 1 Diabetes

Expression Levels of the Growth-Arrest-Specific Transcript 5 in Overweight and Obese Children and Adolescents

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